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Nat Neurosci 4 : 10861092

Eric Topol, a research methods expert and director of Scripps Research Translational Institute

Detoxification: NAC aids in detoxification by supporting liver function and enhancing the elimination of heavy metals and other toxins

Disruption of cysteine uptake and collapse of intracellular GSH pool induces an inhibition of the detoxifying activity of GPx4 and excessive accumulation of oxidatively damaged lipids at the membrane, although it remains unclear if this solely affects the cell plasma membrane, or the effect also extends to organelle membranes

One of the biggest challenges with glutathione is that it is notoriously difficult to absorb

Beijing: China Medical Science Press